Cardiac Resynchronization Therapy and Left Ventricular Diastolic Function

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Cardiac resynchronization therapy acutely improves diastolic function.

BACKGROUND Invasive studies have shown that cardiac resynchronization therapy (CRT) acutely improves left ventricular (LV) systolic performance and lowers filling pressures in a majority of patients with medically-refractory severe heart failure. Measurements included LV volume, ejection fraction, PWD early (E-wave) and atrial (A-wave) velocities, diastolic filling time (DFT), and DTI early dia...

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Relation of left ventricular lead placement in cardiac resynchronization therapy to left ventricular reverse remodeling and to diastolic dyssynchrony.

The effects of left ventricular (LV) lead placement for cardiac resynchronization therapy (CRT) on LV remodeling and dyssynchrony are not well defined. Sixty-one patients (age 60 +/- 11 years, 76% men) were evaluated by echocardiography before and 4 +/- 2 months after CRT and grouped by the LV lead placement (lateral, posterolateral, or anterolateral). Echocardiographic measurements included LV...

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Influence of Diabetes on Left Ventricular Systolic and Diastolic Function and on Long-Term Outcome After Cardiac Resynchronization Therapy

OBJECTIVE The influence of diabetes on cardiac resynchronization therapy (CRT) remains unclear. The aims of the current study were to 1) assess the changes in left ventricular (LV) systolic and diastolic function and 2) evaluate long-term prognosis in CRT recipients with diabetes. RESEARCH DESIGN AND METHODS A total of 710 CRT recipients (171 with diabetes) were included from an ongoing regis...

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Clinical outcomes after cardiac resynchronization therapy: importance of left ventricular diastolic function and origin of heart failure.

BACKGROUND Cardiac resynchronization therapy (CRT) improves functional outcomes in patients with severe systolic heart failure. Whether the effects of CRT on left ventricular (LV) diastolic function and clinical outcomes are influenced by the cause as either ischemic or nonischemic cardiomyopathy (CM) has not been well established. METHODS A total of 57 patients (age 60 +/- 11 years; 25% wome...

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Left Ventricular Phase Analysis and Outcomes of Cardiac Resynchronization Therapy

Background: Left ventricular dyssynchrony plays an important role in predicting response to Cardiac Resynchronization Therapy (CRT). Methods: Thirty patients underwent CRT implantation. Assessment of Left Ventricular (LV) dyssynchrony was done through Gated Spect LV phase analysis. Results: Thirty patients received CRT (mean age 58.7 ±9.0, 24 males). CRT implantation had a favorable prognosis o...

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ژورنال

عنوان ژورنال: Journal of Clinical & Medical Genomics

سال: 2015

ISSN: 2472-128X

DOI: 10.4172/2472-128x.1000118